Virus of Pekin ducks with structural and biological relatedness to human hepatitis B virus
- 1 December 1980
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 36 (3) , 829-836
- https://doi.org/10.1128/jvi.36.3.829-836.1980
Abstract
A virus found in the sera of Pekin ducks appears to be a new member of the human hepatitis B-like family of viruses. This virus had a diameter of 40 nm and an EM appearance similar to that of human hepatitis B virus. The DNA genome of the virus was circular and partially single stranded and an endogenous DNA polymerase associated with the virus was capable of converting the genome to a double-stranded circle with a size of approximately 3000 base pairs. An analysis for viral DNA in the organs of infected birds indicated preferential localization in the liver, implicating this organ as the site of virus replication. In all of these aspects, the virus bears a striking resemblance to human hepatitis B virus and appears to be a new member of this family which also includes ground squirrel hepatitis virus and woodchuck hepatitis virus.This publication has 16 references indexed in Scilit:
- A virus in Beechey ground squirrels that is related to hepatitis B virus of humans.Proceedings of the National Academy of Sciences, 1980
- Cloning in Escherichia coli and physical structure of hepatitis B virion DNA.Proceedings of the National Academy of Sciences, 1979
- HBeAg and anti‐hbe detection by radioimmunoassay: Correlation with vertical transmission of hepatitis B virus in TaiwanJournal of Medical Virology, 1979
- A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks.Proceedings of the National Academy of Sciences, 1978
- Electrophoresis of DNA in agarose gels. Optimizing separations of conformational isomers of double- and single-stranded DNAsBiochemistry, 1977
- E Antigen and Anti-E in the Serum of Asymptomatic Carrier Mothers as Indicators of Positive and Negative Transmission of Hepatitis B Virus to Their InfantsNew England Journal of Medicine, 1976
- The relation of infection with the hepatitis B agent to primary hepatic carcinoma.1975
- Genome of hepatitis B virus: restriction enzyme cleavage and structure of DNA extracted from Dane particles.Proceedings of the National Academy of Sciences, 1975
- CHRONIC LIVER DISEASE AND PRIMARY LIVER-CELL CANCER WITH HEPATITIS-ASSOCIATED (AUSTRALIA) ANTIGEN IN SERUMThe Lancet, 1970
- A nuclease specific for heat-denatured DNA isolated from a product of Aspergillus oryzaeBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1966