Influence of Cold, Fasting and Adrenalectomy on the Blood-Fibrinogen Response to Trauma
- 1 April 1950
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 73 (4) , 611-613
- https://doi.org/10.3181/00379727-73-17761
Abstract
Periods of 24, 48 and 72 hrs. of fasting constantly, though not always significantly, depress the blood-fibrinogen concn. in intact rats. The blood-fibrinogen response to trauma is unaffected by fasting periods of 48 and 72 hrs. Simultaneous exposure to cold and fasting significantly reduces the fibrinogen rise induced by trauma. Total adrenalectomy greatly decreases but does not abolish the fibrinogen response to injury. However, the blood-fibrinogen increase following an operation is prolonged in totally adren-alectomized as compared to partially adrenalectomized rats. These observations suggest that the adrenals play an important role in fibrinogen metabolism.Keywords
This publication has 6 references indexed in Scilit:
- REGULATION OF ENDOGENOUS CORTIN PRODUCTIONEndocrinology, 1947
- REGULATION OF PITUITARY ADRENOCORTICOTROPHIC ACTIVITY DURING THE RESPONSE OF THE RAT TO ACUTE STRESS1Endocrinology, 1947
- THE EFFECT OF BETA-CHLOROETHYL VESICANTS, THERMAL INJURY, AND TURPENTINE ON PLASMA FIBRIN, CHOLESTEROL, AND SUGAR OF DOGS AND RATS1947
- PLASMA PROTEIN METABOLISM—ELECTROPHORETIC STUDIESThe Journal of Experimental Medicine, 1945
- BLOOD PLASMA PROTEIN GIVEN BY VEIN UTILIZED IN BODY METABOLISMThe Journal of Experimental Medicine, 1934
- BLOOD FIBRIN STUDIESAmerican Journal of Physiology-Legacy Content, 1930