Thromboembolic Complications, Heparin Treatment and Increase in Coagulation Factors in Cushing's Syndrome
- 12 January 1976
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 199 (1-6) , 95-98
- https://doi.org/10.1111/j.0954-6820.1976.tb06697.x
Abstract
Seven of 19 consecutive patients with Cushing''s syndrome demonstrated thromboembolic manifestations before or after adrenalectomy. These were successfully treated with heparin. The mean values of coagulation factors VIII (AHF) and V as well as prothrombin were increased. There was a positive correlation between the increase in factor VIII content and the severity of disease. The possibility that these changes in blood coagulation activity reflect an increased coagulability state in Cushing''s syndrome is dicussed.This publication has 25 references indexed in Scilit:
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