EFFECT OF TEMPERATURE UPON THE GLUCOSE TOLERANCE OF THE EVISCERATE RAT

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Abstract
The tolerance of eviscerate male rats for glucose admd. by constant intraven. injn. was studied over a temp. range of 24-38[degree]C for a period of 3 hrs. The poikilo-thermic behavior of eviscerate rats was confirmed and under these conditions there was a close correlation between the temp. of the surrounding air and the glucose load which the rat was able to tolerate. In expt, I, rats were given glucose with insulin. At a temp. of 24[degree]C, tolerance was represented by a glucose load of 60 mg. of glucose per 100 g. of rat per hr. (60/100/hr.). At 38[degree]C, tolerance was represented by a glucose load of 150/100/hr. In expt. n, rats were given glucose without insulin. At 26[degree]C, the glucose load of 10/100/hr. best represented tolerance and at 38[degree]C, the glucose load which best represented tolerance was 22/100/hr.