Ginkgo biloba for Preventing Cognitive Decline in Older AdultsA Randomized Trial
Open Access
- 23 December 2009
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 302 (24) , 2663-2670
- https://doi.org/10.1001/jama.2009.1913
Abstract
Ginkgo biloba is marketed widely and used with the hope of improving, preventing, or delaying cognitive impairment associated with aging and neurodegenerative disorders such as Alzheimer disease. The primary outcome analysis from the Ginkgo Evaluation of Memory (GEM) study, the largest completed randomized, double-blind, placebo-controlled dementia prevention trial to date,1 found that G biloba, 120 mg twice daily, was not effective in reducing the incidence of Alzheimer dementia or dementia overall.Keywords
This publication has 31 references indexed in Scilit:
- Identifying mild cognitive impairment at baseline in the Ginkgo Evaluation of Memory (GEM) studyAging & Mental Health, 2009
- Ginkgo biloba for cognitive impairment and dementiaCochrane Database of Systematic Reviews, 2009
- Ginkgo biloba for Prevention of DementiaA Randomized Controlled TrialJAMA, 2008
- A randomized placebo-controlled trial of Ginkgo biloba for the prevention of cognitive declineNeurology, 2008
- The Ginkgo Evaluation of Memory (GEM) study: Design and baseline data of a randomized trial of Ginkgo biloba extract in prevention of dementiaContemporary Clinical Trials, 2006
- Neuropsychological characteristics of mild cognitive impairment subgroupsJournal of Neurology, Neurosurgery & Psychiatry, 2006
- Improved haemorrheological properties by Ginkgo biloba extract (Egb 761) in type 2 diabetes mellitus complicated with retinopathyClinical Nutrition, 2004
- Comprehensive and Neuropsychologic EvaluationsInternational Psychogeriatrics, 1996
- Normal Rates of Forgetting of Verbal and Non-Verbal Material in Alzheimer's DiseaseCortex, 1987
- A New Clinical Scale for the Staging of DementiaThe British Journal of Psychiatry, 1982