Gradually Increasing Doses of Prednisone in Myasthenia Gravis
- 10 January 1974
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 290 (2) , 81-84
- https://doi.org/10.1056/nejm197401102900204
Abstract
ACTH and adrenal corticosteroids are effective in the treatment of myasthenia gravis. However, increased weakness may occur early in treatment, posing a considerable risk for the patient. To determine whether the early weakening could be avoided by use of a gradually increasing dosage schedule, we started treatment with 25 mg of prednisone on alternate days, and gradually increased the dose to 100 mg on alternate days. Anticholinesterase medication was maintained.Keywords
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