Occurrence of Adenovirus-SV40 Hybrids Among Monkey Kidney Cell Adapted Strains of Adenovirus.
- 1 May 1966
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 122 (1) , 214-218
- https://doi.org/10.3181/00379727-122-31093
Abstract
Summary The strains of adenovirus types 1 through 5 adapted to rhesus monkey kidney cultures for use in vaccines became contaminated with SV40 virus and formed hybrids, carrying SV40 genetic material in adenovirus capsids in a manner similar to that seen in Ad. 7 strain LLE46. The ability of the strains studied here to propagate in monkey cells (with the possible exception of type 5) is dependent on the SV40 genetic material and is not due to emergence of monkey-adapted adenovirus mutants.This publication has 1 reference indexed in Scilit:
- A SPECIFIC COMPLEMENT-FIXING ANTIGEN PRESENT IN SV40 TUMOR AND TRANSFORMED CELLSProceedings of the National Academy of Sciences, 1963