High Continuous Antimony Therapy in Two Patients with Unresponsive Mucosal Leishmaniasis
- 1 July 1985
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 34 (4) , 710-713
- https://doi.org/10.4269/ajtmh.1985.34.710
Abstract
The treatment of two patients with severe mucosal leishmaniasis due to Leishmania braziliensis braziliensis is described. Both patients had received much prior antimonial therapy and one had relapsed after a total dose of 2.5 g of Amphotericin B. Both patients responded to prolonged continuous Pentostam therapy at a daily dose of 20 mg Sbv/kg/day for 62 days in one case and for 85 days in the other. Pentavalent antimonials can be curative in such protracted courses in selected patients unresponsive to standard chemotherapy.This publication has 4 references indexed in Scilit:
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- APPARENT GLUCANTIME FAILURE IN 5 PATIENTS WITH MUCOCUTANEOUS LEISHMANIASIS1980