Paediatric Pharmacology
Open Access
- 1 November 1973
- journal article
- research article
- Published by SAGE Publications in Anaesthesia and Intensive Care
- Vol. 1 (6) , 473-479
- https://doi.org/10.1177/0310057x7300100605
Abstract
Infants and children differ pharmacologically from adults because the progressive maturation of various systems during development leads to variations in drug action and dosage. These differences are reviewed. Pharmacogenetic factors which affect anaesthesia and the problems of drug overdosage, as seen in paediatric intensive care units, are briefly considered.Keywords
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