THE AMINOACYL-TRANSFER RNA POPULATION OF HUMAN RETICULOCYTES

  • 1 January 1982
    • journal article
    • research article
    • Vol. 257  (6) , 3183-3188
Abstract
The aminoacyl-tRNA population of human reticulocytes was examined. These studies include: determination of the levels of amino acid acceptance for 20 aminoacyl-tRNA; comparison of 20 aminoacyl-tRNA from human reticulocytes to those of rabbit reticulocytes by reverse phase chromatography; comparisons of the levels of Ile- and Leu-tRNA in fetal and adult reticulocytes; and determination of the codon recognition properties of human Ala-, Asn-, His-, Leu-, Thr- and Val-tRNA. These studies provide evidence that the aminoacyl-tRNA population of human reticulocytes is adapted to the requirements of protein synthesis.