Constitutive Connective Tissue Growth Factor Expression in Scleroderma Fibroblasts Is Dependent on Sp1
Open Access
- 1 October 2003
- journal article
- Published by Elsevier
- Vol. 278 (43) , 41728-41733
- https://doi.org/10.1074/jbc.m305019200
Abstract
No abstract availableKeywords
This publication has 38 references indexed in Scilit:
- Prostacyclin derivatives prevent the fibrotic response to TGFβ2 by inhibiting the Ras/MEK/ERK pathwayThe FASEB Journal, 2002
- Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-βNature Cell Biology, 2002
- Blocking Sp1 Transcription Factor Broadly Inhibits Extracellular Matrix Gene Expression In Vitro and In Vivo: Implications for the Treatment of Tissue FibrosisJournal of Investigative Dermatology, 2001
- Connective Tissue Growth Factor: What's in a Name?Molecular Genetics and Metabolism, 2000
- Role of Transforming Growth Factor β in Human DiseaseNew England Journal of Medicine, 2000
- Expression of TGF-β1, -β2 and -β3 in localized and systemic sclerodermaJournal of Dermatological Science, 1999
- Dephosphorylation of Sp1 by Protein Phosphatase 1 Is Involved in the Glucose-mediated Activation of the Acetyl-CoA Carboxylase GenePublished by Elsevier ,1996
- Direct demonstration of transcriptional activation of collagen gene expression in systemic sclerosis fibroblasts: Insensitivity to TGFβ1 stimulationBiochemical and Biophysical Research Communications, 1992
- Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10.The Journal of cell biology, 1991
- Transcription and Expression of Transforming Growth Factor Type Beta in the Skin of Progressive Systemic Sclerosis: A Mediator of Fibrosis?Journal of Investigative Dermatology, 1990