Inhibitors of cyclic adenosine 3',5'-monophosphate phosphodiesterase in Phyllostachys nigra MUNRO var. henonis STAPF. and Phragmites communis TRIN., and inhibition by related compounds.
- 1 January 1984
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 32 (2) , 578-584
- https://doi.org/10.1248/cpb.32.578
Abstract
CAMP phosphodiesterase inhibitors present in the culms of Phyllostachys nigra var. henonis and the rhizomes of Phragmites communis (Gramineae) were identified as 2,5-dimethoxy-p-benzoquinone, p-hydroxybenzaldehyde, syringaldehyde, coniferylaldehyde, vanilic acid, ferulic acid and p-coumaric acid. The structure-activity relationship was investigated with 12 derivatives of p-benzoquinone, 22 derivatives of benzaldehyde, 10 derivatives of benzyl alcohol, 24 derivatives of benzoic acid and 32 derivatives of C6-C3 related compounds.This publication has 3 references indexed in Scilit:
- Inhibition of Cyclic AMP Phosphodiesterase by FlavonoidsPlanta Medica, 1982
- Inhibitors of cyclic adenosine monophosphate phosphodiesterase in Polygala tenuifolia.CHEMICAL & PHARMACEUTICAL BULLETIN, 1982
- Inhibition of cyclic AMP phosphodiesterase by lignans.CHEMICAL & PHARMACEUTICAL BULLETIN, 1981