V-Phaser 2: variant inference for viral populations
Open Access
- 1 January 2013
- journal article
- Published by Springer Nature in BMC Genomics
- Vol. 14 (1) , 674
- https://doi.org/10.1186/1471-2164-14-674
Abstract
Massively parallel sequencing offers the possibility of revolutionizing the study of viral populations by providing ultra deep sequencing (tens to hundreds of thousand fold coverage) of complete viral genomes. However, differentiation of true low frequency variants from sequencing errors remains challenging.Keywords
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