Oral Tetrahydroaminoacridine in the Treatment of Senile Dementia, Alzheimer's Type
- 18 June 1987
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 316 (25) , 1603-1605
- https://doi.org/10.1056/nejm198706183162512
Abstract
To the Editor: The report by Summers et a!. (Nov. 13 issue)* contains methodologic problems that render the results difficult to interpret.First, the selection of outcome variables is inappropriate. The neuropsychological assessment techniques employed included the Luria–Nebraska Neuropsychological Test, the Minnesota Multiphasic Personality Inventory, the New York University Memory Test, Wechsler's Adult Intelligence Scale, the Mini Mental State test, three psychometric tests, and a subjective measure designed by the authors. The authors do not refer to the results of any tests except the four they designed.The psychometric properties and construct validity of these psychometric scales are unknown. It . . .Keywords
This publication has 14 references indexed in Scilit:
- Isolation and the fluorometric, high-performance liquid chromatographic determination of tacrineAnalytical Biochemistry, 1986
- Oral Tetrahydroaminoacridine in Long-Term Treatment of Senile Dementia, Alzheimer TypeNew England Journal of Medicine, 1986
- The Cholinergic Neurotransmitter System in Human Memory and Dementia: A ReviewThe Quarterly Journal of Experimental Psychology Section A, 1986
- Naloxone and Alzheimer's DiseaseArchives of General Psychiatry, 1986
- PHARMACOLOGICAL TREATMENTS OF DEMENTIA (NON-CHOLINERGIC)British Medical Bulletin, 1986
- Evaluation of Zimeldine in Alzheimer's DiseaseArchives of Neurology, 1985
- Antidepressants in states of cognitive dysfunctionDrug Development Research, 1984
- Cholinesterase Inhibitors and Opiate Antagonists in Patients with Alzheimer's DiseaseNew England Journal of Medicine, 1983
- No effect from double‐blind trial of physostigmine and lecithin in Alzheimer diseaseAnnals of Neurology, 1983
- Reporting on Methods in Clinical TrialsNew England Journal of Medicine, 1982