North of England evidence based guideline development project: summary guideline for non-steroidal anti-inflammatory drugs versus basic analgesia in treating the pain of degenerative arthritis
- 22 August 1998
- Vol. 317 (7157) , 526-530
- https://doi.org/10.1136/bmj.317.7157.526
Abstract
Other members of the guideline development and project groups are listed in the Appendix This guideline addresses the appropriate use of non-steroidal anti-inflammatory drugs in the primary care treatment of patients with joint pain believed to be caused by degenerative arthritis. It does not consider therapies other than drug treatment. General practitioners must use their professional knowledge and judgement when applying guideline recommendations to the management of individual patients. They should note the information, contraindications, interactions, and side effects contained in the British National Formulary.1 This is a summary of the full version of the guideline.2 In this article, the statements accompanied by categories of evidence (cited as Ia, Ib, IIa, IIb, III, and IV) and recommendations classified according to their strength (A, B, C, or D) are as described previously and are summarised in the box.3 ### Summary points The methods used to develop the guideline have been described previously.3Briefly, we searched the electronic databases Medline and Embase, using a combination of subject heading and free text terms aimed at locating systematic reviews, meta-analyses, randomised trials, quality of life studies, and economic studies. The search was backed up by the expert knowledge and experience of group members. ### Strength of recommendationKeywords
This publication has 14 references indexed in Scilit:
- North of England evidence based guidelines development project: methods of developing guidelines for efficient drug use in primary careBMJ, 1998
- Systematic overview of co-proxamol to assess analgesic effects of addition of dextropropoxyphene to paracetamolBMJ, 1997
- Prevention of Nonsteroidal Anti-inflammatory Drug—Induced Gastrointestinal Mucosal InjuryArchives of internal medicine (1960), 1996
- Analgesic efficacy and safety of paracetamol-codeine combinations versus paracetamol alone: a systematic reviewBMJ, 1996
- Variability in risk of gastrointestinal complications with individual non-steroidal anti-inflammatory drugs: results of a collaborative meta-analysisBMJ, 1996
- Misoprostol Reduces Serious Gastrointestinal Complications in Patients with Rheumatoid Arthritis Receiving Nonsteroidal Anti-Inflammatory DrugsAnnals of Internal Medicine, 1995
- Comparison of naproxen and acetaminophen in a two‐year study of treatment of osteoarthritis of the kneeArthritis & Rheumatism, 1993
- Methodology and overt and hidden bias in reports of 196 double-blind trials of nonsteroidal antiinflammatory drugs in rheumatoid arthritisControlled Clinical Trials, 1989
- Joint pain and quality of life; results of a randomised trial.British Journal of Clinical Pharmacology, 1989
- Prevention of gastroduodenal damage induced by non-steroidal anti-inflammatory drugs: controlled trial of ranitidine.BMJ, 1988