Liver damage in a neonate with alpha-1-antitrypsin deficiency due to phenotype PiZ null (Z-)
- 31 March 1982
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 57 (4) , 311-313
- https://doi.org/10.1136/adc.57.4.311
Abstract
An infant with neonatal liver damage had α-1-antitrypsin deficiency, having inherited the Z allele from the father and the rare null allele from the mother. This indicates that while a lack of serum antiprotease predisposes to early liver disease, homozygosity for the Z allele is not essential.Keywords
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