Studies on Hypothermia by Means of a Pump-Oxygenator

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Abstract
A pump- oxygenator based on the principle of gas dispersion was used in 33 dogs to produce rapid changes in body temp. Blood pressure, respiratory rate, heart rate and ecg. tracings resembled the changes seen in immersion hypothermia. During cooling, available blood flow in the venous catheters showed marked reduction which could not be influenced by the admn. of intraven. fluid. Rewarming restored blood flow to precooling levels. By shunting oxygenated blood equivalent to the cardiac output from the right heart into the aorta, acute cardiac crisis did not occur during the perfusion. All dogs cooled to 29 0C survived, there was a rising mortality from 29 to 27[degree] and all animals below 27[degree] died of ventricular fibrillation as a complication of cardiac catheterization during hypothermia.

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