Abstract
A method is described by which, in the absence of O, the "initial" heat-production in a muscle twitch can be compared with the "total" heat-production. The 2 are found to be very nearly equal. Hence, in a muscle twitch, there is little or no delayed anaerobic heat-production. Since lactic acid can not be formed without heat-production, it follows that there is no delayed lactic acid formation; the lactic acid must appear entirely during contraction and relaxation. The contrary conclusion of Embden, Lehnartz and Hentschel, the experimental basis of whose work has been criticized by Meyerhof and Schulz, is shown to rest on imperfect reasoning; the method they adopted could not decide the question.

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