Fibrinolytic Activity in Men with Acute Myocardial Infarction before 60 Years of Age

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Abstract
Fibrinolytic activity in plasma after venous occlusion was determined on two consecutive days 1–5 years after an acute myocardial infarction sustained before the age of 60 years in a group of 66 non‐diabetic men with normal serum cholesterol levels, and in an age‐ and sex‐matched reference group of 32 men. The infarction group was divided into 2 subgroups: one with normal (n = 42), the other with elevated (n = 24) diastolic blood pressure. Variance analysis did not reveal any statistically significant differences in fibrinolytic activity after repeated provocation between the three groups, but in a Student's test the value was significantly lower in the infarction group with high diastolic pressure than in the reference group. A relationship was found between apolipoprotein AI and fibrinolytic activity after repeated provocation.