A Single-Column Procedure on Bond Elut Certify for Systematic Toxicological Analysis of Drugs in Plasma and Urine
- 1 January 1992
- journal article
- Published by ASTM International in Journal of Forensic Sciences
- Vol. 37 (1) , 61-71
- https://doi.org/10.1520/jfs13211j
Abstract
A single-column solid-phase extraction procedure was developed for the screening of acidic, neutral, and basic drugs from plasma. The recoveries of all 25 tested drugs exceeded 82%. After the plasma had been diluted with phosphate buffer (pH 6.0), the druKeywords
This publication has 11 references indexed in Scilit:
- Rapid Screening for 100 Basic Drugs and Metabolites in Urine Using Cation Exchange Solid-Phase Extraction and High-Performance Liquid Chromatography with Diode Array DetectionJournal of Analytical Toxicology, 1990
- Solid-phase extraction for the screening of acidic, neutral and basic drugs in plasma using a single-column procedure on Bond Elut CertifyJournal of Chromatography B: Biomedical Sciences and Applications, 1990
- A SepPak® HPLC Method for Tricyclic Antidepressant Drugs in Human Vitreous HumorJournal of Analytical Toxicology, 1989
- Sample preparation for biomedical analysisJournal of Chromatography B: Biomedical Sciences and Applications, 1989
- Analysis of benzodiazepines and tricyclic antidepressants in serum using a common solid-phase clean-up and a common mobile phaseJournal of Chromatography B: Biomedical Sciences and Applications, 1989
- Biological Sample Preparation and Data Reduction Concepts in Pharmaceutical AnalysisJournal of Chromatographic Science, 1988
- Isolation of basic drugs from plasma using solid-phase extraction with a cyanopropyl-bonded phaseJournal of Chromatography B: Biomedical Sciences and Applications, 1988
- High-performance liquid chromatographic determination of triazolam and its metabolites in human urineJournal of Chromatography B: Biomedical Sciences and Applications, 1987
- Determination of temazepam in plasma and urine by high-performance liquid chromatography using disposable solid-phase extraction columnsJournal of Pharmaceutical and Biomedical Analysis, 1986
- A rapid and reliable method for extraction and assay of tricyclic antidepressant drugs in serum or plasmaBiomedical Chromatography, 1986