Base specific binding of deoxyguanylate and deoxycytidylate antibodies to double stranded DNA
Open Access
- 1 January 1982
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 10 (20) , 6273-6280
- https://doi.org/10.1093/nar/10.20.6273
Abstract
Antibodies raised in rabbits against daoxyguanylate and daoxycytidylate bind to 3H-λ double stranded DNA and the binding is base specific. The concentrations of antibody populations that bind to double stranded DNA are much less than those binding to denatured DNA. Due to their low concentrations, these antibodies ware not detected in earlier studies. These antibodies are expected to be useful to probe the conformational flexibilities of double stranded DNAs.Keywords
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