α CÉTOPHOSPHONATES ET ESTERS CYCLIQUES D'HYDROXYMÉTHYLÈNES DIPHOSPHONATES SYNTHESES, STRUCTURES ET HYDROLYSE
- 1 June 1986
- journal article
- research article
- Published by Taylor & Francis in Phosphorus and Sulfur and the Related Elements
- Vol. 27 (3) , 301-312
- https://doi.org/10.1080/03086648608072784
Abstract
Synthesis of symmetrical diesters derived from hydroxy methylene diphosphonic acids 1 to 8 is described either in one step or via the corresponding α ketophosphonate 1a to 8a. Study of the diphosphonates (1 to 6) → phosphate-phosphonates (1b to 6b) isomerization has been realized. Results related to peculiar cases in connection with nonsymmetrical esters 10, 11, 17 and study of the hydrolysis reaction of diphosphonates are presented.Keywords
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