Site-directed mutagenesis of recombinant human arylamine N-acetyltransferase expressed in Escherichia coli. Evidence for direct involvement of Cys68 in the catalytic mechanism of polymorphic human NAT2.

This publication has 21 references indexed in Scilit:

• An arylamine acetyltransferase (AT‐I) from syrian golden hamster liver: Cloning, complete nucleotide sequence, and expression in mammalian cells
  Molecular Carcinogenesis, 1991
• Human ArylamineN-Acetyltransferase Genes: Isolation, Chromosomal Localization, and Functional Expression
  DNA and Cell Biology, 1990
• Acetylation pharmacogenetics. The slow acetylator phenotype is caused by decreased or absent arylamine N-acetyltransferase in human liver.
  Journal of Clinical Investigation, 1990
• Evidence for two closely related isozymes of arylamine N‐acetyltransferase in human liver
  FEBS Letters, 1989
• N-acetyltransferase
  Pharmacology & Therapeutics, 1989
• Enhanced protein thermostability from site-directed mutations that decrease the entropy of unfolding.
  Proceedings of the National Academy of Sciences, 1987
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
  Analytical Biochemistry, 1976
• The mechanism of isoniazid acetylation by human N-acetyltransferase
  Biochimica et Biophysica Acta (BBA) - Enzymology, 1968
• The enzymatic transacetylation between aromatic amines
  Archives of Biochemistry and Biophysics, 1953
• On the Evaluation of the Constants V _m and K _M in Enzyme Reactions
  Science, 1952