Farnesyltransferase inhibitors: antineoplastic properties, mechanisms of action, and clinical prospects
- 31 December 2000
- journal article
- review article
- Published by Elsevier in Seminars in Cancer Biology
- Vol. 10 (6) , 443-452
- https://doi.org/10.1006/scbi.2000.0335
Abstract
No abstract availableKeywords
This publication has 53 references indexed in Scilit:
- Essential role for oncogenic Ras in tumour maintenanceNature, 1999
- THE POTENTIAL OF FARNESYLTRANSFERASE INHIBITORS AS CANCER CHEMOTHERAPEUTICSAnnual Review of Pharmacology and Toxicology, 1997
- Pharmaceutical research in molecular oncologyCell, 1994
- Farnesyltransferase inhibitors: Ras research yields a potential cancer therapeuticCell, 1994
- FUNCTION AND REGULATION OF RASAnnual Review of Biochemistry, 1993
- Human Sos1: a Guanine Nucleotide Exchange Factor for Ras that Binds to GRB2Science, 1993
- Altered Growth of Human Colon Cancer Cell Lines Disrupted at Activated Ki- rasScience, 1993
- Regulators and Effectors of ras ProteinsAnnual Review of Cell Biology, 1991
- Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: Synergistic action of oncogenes in vivoCell, 1987
- Guanine nucleotide-binding and autophosphorylating activities associated with the p21src protein of Harvey murine sarcoma virusNature, 1980