Submolecular resolution of single macromolecules with atomic force microscopy
Open Access
- 23 June 1998
- journal article
- review article
- Published by Wiley in FEBS Letters
- Vol. 430 (1-2) , 51-54
- https://doi.org/10.1016/s0014-5793(98)00461-x
Abstract
The intrinsically high signal‐to‐noise ratio of atomic force microscopy (AFM) permits structural determination of individual macromolecules to, at times, subnanometer resolution directly from unprocessed images, avoiding the conditions and possible consequences of averaging over an ensemble of molecules. In this article, we will review some of the most recent achievements in imaging single macromolecules with AFM.Keywords
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