In situ hybridization localizes the human type II alpha 1 collagen gene (COL2A1) to 12q13
Open Access
- 14 February 2008
- journal article
- research article
- Published by Springer Nature in Hereditas
- Vol. 110 (2) , 165-167
- https://doi.org/10.1111/j.1601-5223.1989.tb00437.x
Abstract
We have, using in situ hybridization technique, localized the human type II alpha 1 collagen gene (COL2A1) to chromosome band 12q13. The gene had previously been assigned to either 12q13.1-13.2 or 12q14.3. Since the chromosome segment 12q13-15 has been shown to be rearranged in several benign and malignant human neoplasms, the exact band localization of COL2A1 within this region makes it a useful marker for the molecular analysis of these tumors.This publication has 25 references indexed in Scilit:
- A specific translocation, t(12;14)(q14–15; q23–24), characterizes a subgroup of uterine leiomyomasCancer Genetics and Cytogenetics, 1988
- Clonal chromosome rearrangements in a uterine myomaCancer Genetics and Cytogenetics, 1988
- Lipomas have characteristic structural chromosomal rearrangements of 12q13‐q14International Journal of Cancer, 1987
- Rearrangements of chromosome region 12q13→q15 in pleomorphic adenomas of the human salivary gland (PSA)Cytogenetic and Genome Research, 1987
- Reciprocal translocation t(3;12)(q27;q13) in lipomaCancer Genetics and Cytogenetics, 1986
- The human type II collagen gene (COL2A1) assigned to 12q14.3Annals of Human Genetics, 1986
- Identification and characterization of the human type II collagen gene (COL2A1).Proceedings of the National Academy of Sciences, 1985
- A technique for radiolabeling DNA restriction endonuclease fragments to high specific activityAnalytical Biochemistry, 1984
- An improved method for G-banding chromosomes after in situ hybridizationCytogenetic and Genome Research, 1984
- Localization of single copy DNA sequences on G-banded human chromosomes by in situ hybridizationChromosoma, 1981