The Drosophila gene torso encodes a putative receptor tyrosine kinase
- 1 April 1989
- journal article
- Published by Springer Nature in Nature
- Vol. 338 (6215) , 478-483
- https://doi.org/10.1038/338478a0
Abstract
The maternal gene torso, required for determination of anterior and posterior terminal structures in the Drosophila embryo, was cloned using P-element tagging. Genetic evidence suggests that the action of the gene product is spatially restricted to the terminal regions; the torso messenger RNA, however, is evenly distributed. Structural similarities of the predicted torso protein with growth-factor receptor tyrosine kinases suggest that the spatial restriction of torso activity results from a localized activation of the torso protein at the anterior and posterior egg pole.Keywords
This publication has 42 references indexed in Scilit:
- Function of torso in determining the terminal anlagen of the Drosophila embryoNature, 1988
- Accumulation and Spatial Distribution of Poly(A)+RNA in Oocytes and Early Embryos of Drosophila melanogasterDevelopment, Growth & Differentiation, 1988
- Determination of Anteroposterior Polarity in DrosophilaScience, 1987
- Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene networkCell, 1986
- Maternal-effect mutations altering the anterior-posterior pattern of the Drosophila embryoWilhelm Roux' Archiv für Entwicklungsmechanik der Organismen, 1986
- X-LINKED FEMALE-STERILE LOCI IN DROSOPHILA MELANOGASTERGenetics, 1986
- Developmental analysis of the torso-like phenotype in Drosophila produced by a maternal-effect locusDevelopmental Biology, 1986
- A pupal lethal mutation with a paternally influenced maternal effect on embryonic development in Drosophila melanogasterDevelopmental Biology, 1985
- Correct developmental expression of a cloned alcohol dehydrogenase gene transduced into the drosophila germ lineCell, 1983
- Molecular cloning of sequences from a drosophila RNA polymerase II locus by P element transposon taggingCell, 1982