Multimodality Imaging of IL-18–Binding Protein-Fc Therapy of Experimental Lung Metastasis
- 30 September 2008
- journal article
- research article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 14 (19) , 6137-6145
- https://doi.org/10.1158/1078-0432.ccr-08-0049
Abstract
Purpose: Interleukin (IL)-18 plays important roles in cancer progression and metastasis. The goal of this study is to identify cell lines that are most sensitive to stand alone IL-18–binding protein (IL-18bp)-Fc treatment, to study the pharmacokinetics and tumor targeting efficiency of IL-18bp-Fc, and to evaluate the efficacy of IL-18bp-Fc in treating breast cancer experimental lung metastasis by multimodality imaging.This publication has 30 references indexed in Scilit:
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