Correlation Between Adhesion of Pseudomonas Aeruginosa Bacteria to Cell Surfaces and the Presence of Some Factors Related to Virulence

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Abstract
Recent isolates of P. aeruginosa strains and 12-mo.-old subcultivated variants of the same strains were assayed for adhesiveness to HEp-2 cells. P. aeruginosa adhesion factors were located both to the bacterial surface and extracellularly. Loss of adhesiveness upon subcultivation could be restituted by adding extracellular factor from the recent isolate. While the extracellular adhesions were neutralized by non-specific serum factors, the surface-bound adhesions of a recent isolate were blocked by antibodies only.