Influence of Protoveratrine on Effect of Vasoactive Drugs
- 1 November 1954
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 87 (2) , 437-439
- https://doi.org/10.3181/00379727-87-21405
Abstract
Protoveratrine enhanced the blood pressure responses to 1-nor-epinephrine and histamine in dogs and cats. This effect failed to occur in animals whose 9th and 10th nerves were sectioned bilaterally or whose spinal cord was transected. It is suggested that the hypotensive effect of protoveratrine is due to induced spontaneous or repetitive firing of baroceptors, which then become less susceptible to further stimulation or inhibition by changes of pressure.Keywords
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