Statin Use before By-Pass Surgery Decreases the Incidence and Shortens the Duration of Postoperative Atrial Fibrillation
- 18 July 2006
- journal article
- Published by S. Karger AG in Cardiology
- Vol. 107 (2) , 117-121
- https://doi.org/10.1159/000094589
Abstract
The aim of the present observational study is to search the incidence of postoperative atrial fibrillation (AF) in patients with or without preoperative statin treatment. The population consisted of 362 consecutive patients (267 on and 95 not on statin). Diabetes mellitus was more frequent in statin group (p = 0.03). Other demographic and procedural variables were similar in the both groups (All p > 0.05). Postoperative AF was less frequent and its duration was shorter in statin group compared to non-statin group (p = 0.03 and 0.0001, respectively). The Kaplan-Meier analysis showed the protective effect of statins against the risk of developing AF (p = 0.01). Statin treatment before the by-pass surgery decreases the incidence and shortens the duration of postoperative AF.This publication has 18 references indexed in Scilit:
- The HMG-CoA reductase inhibitor atorvastatin prevents atrial fibrillation by inhibiting inflammation in a canine sterile pericarditis modelCardiovascular Research, 2004
- Inflammation as a Risk Factor for Atrial FibrillationCirculation, 2003
- Simvastatin Normalizes Autonomic Neural Control in Experimental Heart FailureCirculation, 2003
- Simvastatin Lowers C-Reactive Protein Within 14 DaysCirculation, 2002
- Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)JAMA, 2001
- Inflammation, Pravastatin, and the Risk of Coronary Events After Myocardial Infarction in Patients With Average Cholesterol LevelsCirculation, 1998
- Atrial Fibrillation After Cardiac SurgeryAnnals of Surgery, 1997
- Predictors of Atrial Fibrillation After Coronary Artery SurgeryCirculation, 1996
- A perspective of postoperative atrial fibrillation in cardiac operationsThe Annals of Thoracic Surgery, 1993
- Some comments on ventricular afterloadBasic Research in Cardiology, 1987