Loss of surface IgD by human B lymphocytes during polyclonal activation*
- 1 March 1977
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 7 (3) , 191-193
- https://doi.org/10.1002/eji.1830070316
Abstract
Surface and cytoplasmic immunoglobulins were studied by direct immunofluorescence in pokeweed mitogen-stimulated cultures of human blood lymphocytes. The results compared to those of studies of unstimulated cultures and of fresh normal lymphocytes showed a striking decrease in surface IgD during terminal maturation of B lymphocytes into plasma cells. The number of cells which expressed IgG Fc receptor also decreased, although to a lesser extent.This publication has 9 references indexed in Scilit:
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