Acetylsalicylic Acid: No Chromosome Damage in Human Leukocytes
- 10 July 1970
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 169 (3941) , 198-201
- https://doi.org/10.1126/science.169.3941.198
Abstract
Acetylsalicylic acid was added to cultures of human leukocytes at several time periods over a wide range of concentrations (0.1 to 300.0 micrograms per milliliter). Leukocytes were also cultured from human volunteers during the ingestion of two 300-milligram tablets four times daily (2400 milligrams per day) over a 1-month period. No significant increase in chromosome aberrations was detected in vitro or in vivo.Keywords
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