Mechanism of Competitive Action of Isonicotinic Acid Hydrazide and Vitamin B6.
- 1 April 1955
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 88 (4) , 519-521
- https://doi.org/10.3181/00379727-88-21638
Abstract
On the basis of studies with apotryptophanase, iso-nicotinic acid hydrazide (INH) is assumed to exert its primary competitive effect on the vitamin B6 group by competing with pyridoxal phosphate for the apoenzyme.Keywords
This publication has 3 references indexed in Scilit:
- Effect of Isoniazid on Vitamin B6 Metabolism; Its Possible Significance in Producing Isoniazid Neuritis.Experimental Biology and Medicine, 1954
- Relationship of Pyridoxine and its Derivatives to the Mechanism of Action of Isoniazid.Experimental Biology and Medicine, 1953
- ANTAGONISM OF ISONIAZID BY CERTAIN METABOLITESPublished by Elsevier ,1953