Abstract
THE last three or four decades have seen great progress in the treatment of mental disease by physical means. Syphilis of the brain and pellagra, both of which were formerly responsible for many admissions to mental hospitals, are no longer serious problems in America, owing to the development of specific cures for them. Insulin and electroshock have been useful in the treatment of manic-depressive and, to a lesser extent, schizophrenic psychoses. Hormones also have been helpful in patients with depressions1 or with post-partum psychoses.2 A few years ago two chemical agents, chlorpromazine and reserpine, were introduced; they have already changed . . .

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