FluoMar, a Fluorous Version of the Marshall Resin for Solution-Phase Library Synthesis
- 4 March 2003
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 5 (7) , 1015-1017
- https://doi.org/10.1021/ol0274864
Abstract
The fluorous counterpart of the Marshall resin, 4-(1H,1H,2H,2H-perfluorodecylsulfanyl)phenol (FluoMar), is prepared by S-alkylation of 4-mercaptophenol with C8F17CH2CH2I and employed in the synthesis of amide and diamide analogues. The final products are purified by solid-phase extraction (SPE) over FluoroFlash silica cartridges.Keywords
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