High-speed three-dimensional X-ray computed tomography: The dynamic spatial reconstructor

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Abstract
Most X-ray CT scanners require a few seconds to produce a single two-dimensional (2-D) image of a cross section of the body. The accuracy of full three-dimensional (3-D) images of the body synthesized from a contiguous set of 2-D images produced by sequential CT scanning of adjacent body slices is limited by 1) slice-to-slice registration (positioning of patient); 2) slice thickness; and 3) motion, both voluntary and involuntary, which occurs during the total time required to scan all slices. Therefore, this method is inadequate for true dynamic 3-D imaging of moving organs like the heart, lungs, and circulation. To circumvent these problems, the Dynamic Spatial Reconstructor (DSR) was designed by the Biodynamics Research Unit at the Mayo Clinic to provide synchronous volume imaging, that is stop-action (1/100 s), high-repetition rate (up to 60/s), simultaneous scanning of many parallel thin cross sections (up to 240, each 0.45 mm thick, 0.9 mm apart) spanning the entire anatomic extent of the bodily organ(s)of interest. These capabilities are achieved by using multiple X-ray sources and multiple 2-D fluoroscopic video camera assemblies on a continually rotating gantry. Desired tradeoffs between temporal, spatial, and density resolution can be achieved by retrospective selection and processing of appropriate subsets of the total data recorded during a continuous DSR scan sequence.