Effect of Certain Stabilizers on Photobleacing of Riboflavin Solutions
- 1 January 1990
- journal article
- research article
- Published by Taylor & Francis in Drug Development and Industrial Pharmacy
- Vol. 16 (1) , 149-156
- https://doi.org/10.3109/03639049009115991
Abstract
The influence of certain stabilizers on the aerobic photobleaching of buffered riboflavin phosphate solutions exuosed to fluorescent light was investigated. Disodium ethylenediamine (EDTA) demonstrated the greatest stabilizing effect followed by thiourea, methyl paraben, DL-methionine and sodium thiosul fate. The photostabilizing effect of these agents increased as their concentrations increased. Other stabilizers enhanced the photostability of riboflavin solutions with lesser and varying degrees. The pH and buffer species of the solutions appared to infulence the rate of photodegradation of riboflavin solutions in the presence of absence of EDTA.This publication has 13 references indexed in Scilit:
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