INSULIN AND GROWTH HORMONE SECRETION IN A LEUKAEMIC GIRL WITH HYPOTHALAMIC SYNDROME
- 1 March 1977
- journal article
- research article
- Published by Wiley in Acta Paediatrica
- Vol. 66 (2) , 261-263
- https://doi.org/10.1111/j.1651-2227.1977.tb07846.x
Abstract
Schilirò, G., Russo, A., Sciotto, A. and Vigo, R. (Paediatric Clinics I and II, University of Catania, Catania, Italy). Insulin and growth hormone secretion in a leukaemic girl with hypothalamic syndrome. Acta Paediatr Scand, 66:261, 1977.—The authors report a girl with acute lymphoblastic leukaemia presenting hypothalamic syndrome characterized by meningeal leukaemia, hyperphagia and obesity. Insulin and growth hormone secretion, studied with arginine and insulin stimulation tests, showed a high peak of serum insulin and no response of growth hormone. Insulin and growth hormone responses to these tests reverted to normal after intrathecal methotrexate.Keywords
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