Specificity mapping of patients IgE response towards the tree pollen major allergens Aln g I, Bet v I and Cor a I
- 1 March 1992
- journal article
- research article
- Published by Wiley in Clinical and Experimental Allergy
- Vol. 22 (3) , 391-399
- https://doi.org/10.1111/j.1365-2222.1992.tb03101.x
Abstract
The specificity pattern of IgE from non-treated tree pollen allergic patients (n = 38) were evaluated by solid phase absorption of serum samples followed by CRIE on alder, birch and hazel CIE precipitation profiles. The majority of the serum samples seemed to contain IgE antibodies with the following characteristics: specific towards Bet v I alone and common between Aln g I, Bet v I and/or Cor a I, 'II'. The IgE specificity profiles observed for 95% of the sera tested are compatible with birch pollen allergens being the only sensitizing allergens, indicating that the patients react to allergens from other tree pollens of the Fagales order due to IgE cross-reaction with the major allergens of birch and alder and/or hazel pollens.Keywords
This publication has 48 references indexed in Scilit:
- Group V allergens in grass pollens. II. Investigation of group V allergens in pollens from 10 grassesClinical and Experimental Allergy, 1991
- Cloning sequencing of Lol pI, the major allergenic protein of rye‐grass pollenFEBS Letters, 1991
- Isolation and characterization of a major cross-reactive grass group I allergenic determinantMolecular Immunology, 1989
- Immunotherapy with partially purified and standardized tree pollen extractsAllergy, 1988
- Cross-reactive and unique grass group I antigenic determinants defined by monoclonal antibodiesJournal of Allergy and Clinical Immunology, 1987
- Specific IgE response toward allergenic molecules during perennial hyposensitization: a three year prospective double-blind studyJournal of Allergy and Clinical Immunology, 1983
- Comparative Studies on Tree Pollen AllergensInternational Archives of Allergy and Immunology, 1982
- Comparative Studies on Tree-Pollen AllergensInternational Archives of Allergy and Immunology, 1981
- Antigens and Allergens in Birch Pollen ExtractAllergy, 1979
- Separation and Characterization of Birch Pollen Antigens with Special Reference to the Allergenic ComponentsInternational Archives of Allergy and Immunology, 1972