Immunoglobulin deposits in the biliary remnants of extrahepatic biliary atresia: a study by immunoperoxidase staining in 128 infants

Abstract
Bile duct remnants taken from 128 [human] infants during surgery for extrahepatic biliary atresia were paraffin embedded prior to immunoperoxidase staining. Ig deposits were found in 44 remnants. They were made up of IgM alone in 25 cases and of IgM and IgG in 19. Deposits were observed along the basement membranes of glandular structures. Extrahepatic biliary atresia may be an acquired and evolving disease.