Abnormal regulation of the LDL-R and HMG CoA reductase genes in subjects with familial hypercholesterolemia with the “French Canadian Mutation”
- 31 July 1996
- journal article
- Published by Elsevier in Atherosclerosis
- Vol. 124 (1) , 103-117
- https://doi.org/10.1016/0021-9150(96)05828-5
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in human mononuclear leukocytes is regulated coordinately and parallels gene expression in human liver.Journal of Clinical Investigation, 1994
- Heroic gene surgeryNature Genetics, 1994
- Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1992
- Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase synthesis in Syrian hamster C100 cells by mevinolin, 25-hydroxycholesterol, and mevalonate: The role of posttranscriptional controlSomatic Cell and Molecular Genetics, 1992
- mRNA quantitation by a simple and sensitive RNAse protection assayGenetic Analysis: Biomolecular Engineering, 1991
- Low-density lipoprotein plasmaphaeresis with and without lovastatin in the treatment of the homozygous form of familial hypercholesterolaemiaEuropean Journal of Pediatrics, 1990
- Familial defective apolipoprotein B-100. Comparison with familial hypercholesterolemia in 18 cases detected in Munich.Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 1990
- Regulation of the mevalonate pathwayNature, 1990
- Identification of a second “French Canadian” LDL receptor gene deletion and development of a rapid method to detect both deletionsClinical Genetics, 1989
- Deletion in the Gene for the Low-Density-Lipoprotein Receptor in a Majority of French Canadians with Familial HypercholesterolemiaNew England Journal of Medicine, 1987