TwoSalmonellaOmpC Kb-Restricted Epitopes for CD8+-T-Cell Recognition
Open Access
- 1 May 2004
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 72 (5) , 3059-3062
- https://doi.org/10.1128/iai.72.5.3059-3062.2004
Abstract
We report the identification of two peptides fromSalmonellaOmpC porin that can bind to major histocompatibility complex class I Kbmolecules and are targets of cytotoxic T lymphocytes fromSalmonella-infected mice. These peptides are conserved in gram-negative bacterial porins and are the firstSalmonellaporin-specific epitopes described for possible CD8+-T-cell elimination of infected cells.Keywords
This publication has 24 references indexed in Scilit:
- ProPred1: prediction of promiscuous MHC Class-I binding sitesBioinformatics, 2003
- Oral Immunization with aSalmonella entericaSerovar Typhi Vaccine Induces Specific Circulating Mucosa-Homing CD4+and CD8+T Cells in HumansInfection and Immunity, 2002
- Salmonella entericaSerovar Typhi Live Vector Vaccines Delivered Intranasally Elicit Regional and Systemic Specific CD8+Major Histocompatibility Class I-Restricted Cytotoxic T LymphocytesInfection and Immunity, 2002
- In Vivo Activation of Dendritic Cells and T Cells duringSalmonella entericaSerovar Typhimurium InfectionInfection and Immunity, 2001
- Macrophages present exogenous antigens by class I major histocompatibility complex molecules via a secretory pathway as a consequence of interferon‐γ activationImmunology, 2001
- Th1 and Th2 cell involvement in immune response to Salmonella typhimurium porinsImmunology, 1998
- Immunogenicity of a Salmonella typhi CVD 908 candidate vaccine strain expressing the major surface protein gp63 of Leishmania mexicana mexicanaVaccine, 1998
- Immunization with live versus killed Salmonella typhimurium leads to the generation of an IFN-γ-dominant versus an IL-4-dominant immune responseInternational Immunology, 1993
- Active protection of mice against Salmonella typhi by immunization with strain-specific porinsVaccine, 1992
- Association of class I major histocompatibility heavy and light chains induced by viral peptidesNature, 1989