Hypokalemic periodic paralysis in Sjogren's syndrome

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Abstract
A 30 yr old woman had scleroderma, Sjogren''s syndrome, deforming polyarthritis, distal renal tubular acidosis, hypokalemic periodic paralysis and persistent mild myopathy. During a 5-yr period the patient''s otherwise mild course of disease was complicated by the occurrence of 5 episodes of severe flaccid muscle paralysis involving both proximal and distal muscle groups. Between the paralytic episodes the patient functioned well without replacement therapy, and had normal K levels. The sicca component was mild and went unrecognized for several years. There was no family history of muscle disease. The paralytic episodes may have been due to hypokalemia secondary to renal tubular acidosis associated with Sjogren''s syndrome. Hypokalemic periodic paralysis may occur as a rare complication of Sjogren''s syndrome and renal tubular acidosis.

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