Novel Bioactive Azaphilones from Fruit Bodies and Mycelial Cultures of the Ascomycete Bulgaria inquinans (Fr.)
- 1 August 1995
- journal article
- research article
- Published by Taylor & Francis in Natural Product Letters
- Vol. 7 (1) , 7-14
- https://doi.org/10.1080/10575639508043180
Abstract
Three new azaphilones, bulgarialactone A (1), B (2) and C (3), were isolated from both the mycelia and fruit bodies of the Ascomycete Bulgaria inquinans. Bulgarialactone A (1) and B (2) possess antimicrobial, cytotoxic and nematicidal activities, and inhibit the binding of 3H-SCH 23390 to the dopamine D1 receptor. The isolation, structure determination and biological activities of the bulgarialactones are reported.Keywords
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