Somatic-cell hybrids producing antibodies against CEA
Open Access
- 1 January 1981
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 43 (1) , 1-4
- https://doi.org/10.1038/bjc.1981.1
Abstract
Monoclonal antibodies to carcinoembryonic antigen (CEA) promise improved specificity for the measurement of this widely expressed human cancer antigen. A mouse monoclonal antibody binds weakly to CEA in perchloric acid extracts of tumour but strongly to CEA similarly isolated from serum, and its spectrum of cancer detection differs from conventional antisera.Keywords
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