Kinetics of local anesthetic inhibition of neuronal sodium currents. pH and hydrophobicity dependence

This publication has 42 references indexed in Scilit:

• Tonic and phasic block of neuronal sodium currents by 5-hydroxyhexano-2',6'-xylide, a neutral lidocaine homologue.
  The Journal of general physiology, 1989
• Review: Quantitative structure/activity relations based on use-dependent block and repriming kinetics in myocardium
  Journal of Molecular and Cellular Cardiology, 1987
• Direct determination by 2H-NMR of the ionization state of phospholipids and of a local anaesthetic at the membrane surface
  Biochimica et Biophysica Acta (BBA) - Biomembranes, 1985
• Altered sodium and gating current kinetics in frog skeletal muscle caused by low external pH.
  The Journal of general physiology, 1984
• A study on the potential-dependence of proton block of sodium channels
  Biochimica et Biophysica Acta (BBA) - Biomembranes, 1984
• New antiarrhythmic agents. 6. Quantitative structure-activity relationships of aminoxylidides
  Journal of Medicinal Chemistry, 1981
• Low intracellular pH and chemical agents slow inactivation gating in sodium channels of muscle
  Nature, 1980
• Sodium Channel Inactivation in Squid Axon Is Removed by High Internal p H or Tyrosine-Specific Reagents
  Science, 1978
• Charges and Potentials at the Nerve Surface
  The Journal of general physiology, 1968
• Elementary Steps in Enzyme Reactions (as Studied by Relaxation Spectrometry)
  Published by Wiley ,1963