Population Pharmacokinetics/Pharmacodynamics Modeling: Parametric and Nonparametric Methods
- 1 June 2000
- journal article
- research article
- Published by Wolters Kluwer Health in Therapeutic Drug Monitoring
- Vol. 22 (3) , 354-365
- https://doi.org/10.1097/00007691-200006000-00019
Abstract
As clinicians acquire experience with the clinical and pharmacokinetic behavior of a drug, it is usually optimal to record this experience in the form of a population pharmacokinetic model, and then to relate the behavior of the model to the clinical effects of the drug or to a linked pharmacodynamic model. The role of population modeling is thus to describe and record clinical experience with the behavior of a drug in a certain group or population of patients or subjects.Keywords
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