Necrotising fasciitis in a patient receiving infliximab for rheumatoid arthritis
- 1 January 2002
- journal article
- case report
- Published by Oxford University Press (OUP)
- Vol. 78 (915) , 47-48
- https://doi.org/10.1136/pmj.78.915.47
Abstract
A case of necrotising fasciitis in a patient receiving infliximab, an antitumour necrosis factor alpha (TNF-α) agent for rheumatoid arthritis, is presented. A widespread confluent, erythematous, pustular skin rash was the presenting sign. There was no fever throughout this admission. β-Haemolytic group A streptococcus was isolated from blood cultures and skin swabs. The adductor muscles and fascia around the site of a previous hip arthroplasty were necrotic on exploration. The case highlights the risk of severe sepsis in patients on anti-TNF-α treatment.Keywords
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