PREVALENCE OF LYME-BORRELIOSIS IN A SWISS RISK POPULATION
- 16 January 1988
- journal article
- research article
- Vol. 118 (2) , 65-69
Abstract
The epidemiology of "Lyme borreliosis" in Europe and the significance of positive antibody titers against Borrelia burgdorferi is not well known. Since "orienteering", a competitive cross country sport with a map and a compass, usually in forests, elevates the risk of being bitten by ticks and infected by Borrelia burgdorferi, nearly 1000 orienteerers were included in a prospective study. In this population the prevalence of positive IgG-antibodies (immunofluorescence technique) was almost 20% and of IgM-antibodies 4%. However, the frequency of associated symptoms in the clinical history of the probands was very low, even in individuals with highly positive titers. We conclude that the rate of asymptomatic Borrelia infections is high in this special group, and probably also in the general population, and that one has therefore to be cautious in interpreting an isolated positive "Lyme titer". Further investigations are needed, and, in particular, follow-up of the many "positive" subjects without clinical symptoms may be helpful in understanding this fascinating disease better.This publication has 12 references indexed in Scilit:
- Longitudinal Assessment of the Clinical and Epidemiological Features of Lyme Disease in a Defined PopulationThe Journal of Infectious Diseases, 1986
- Serologic Testing for Lyme DiseaseAnnals of Internal Medicine, 1985
- Successful Parenteral Penicillin Therapy of Established Lyme ArthritisNew England Journal of Medicine, 1985
- Serological diagnosis of erythema migrans disease and related disordersInfection, 1984
- Antibodies of patients with Lyme disease to components of the Ixodes dammini spirochete.Journal of Clinical Investigation, 1983
- The Spirochetal Etiology of Lyme DiseaseNew England Journal of Medicine, 1983
- Lyme Disease—a Tick-Borne Spirochetosis?Science, 1982
- Lyme Carditis: Cardiac Abnormalities of Lyme DiseaseAnnals of Internal Medicine, 1980
- Chronic Lyme ArthritisAnnals of Internal Medicine, 1979
- Annals of Internal Medicine, 1977